Notable changes to minimap2:
-
Bugfix:
--MD
was not working properly due to the addition of--ds
in the
last release (#1181 and #1182). -
New feature: added an experimental preset
lr:hqae
for aligning accurate
long reads back to their assembly. It has been observed thatmap-hifi
and
lr:hq
may produce many wrong alignments around centromeres when accurate
long reads (PacBio HiFi or Nanopore duplex/Q20+) are mapped to a diploid
assembly constructed from them. This new preset produces much more accurate
alignment. It is still experimental and may be subjective to changes in
future. -
Change: reduced the default
--cap-kalloc
to 500m to lower the peak
memory consumption (#855).
Notable changes to mappy:
- Bugfix: mappy option struct was out of sync with minimap2 (#1177).
Minimap2 should output identical alignments to v2.27.
(2.28: 27 March 2024, r1209)