diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index b912cf46..62765dd9 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -33,7 +33,7 @@ repos:
     hooks:
       - id: verify-alpha-spec
   - repo: https://github.com/rapidsai/dependency-file-generator
-    rev: v1.13.11
+    rev: v1.16.0
     hooks:
         - id: rapids-dependency-file-generator
           args: ["--clean"]
diff --git a/ci/build_cpp.sh b/ci/build_cpp.sh
index 9b419b81..2a347b7e 100755
--- a/ci/build_cpp.sh
+++ b/ci/build_cpp.sh
@@ -17,6 +17,10 @@ rapids-logger "Begin cpp build"
 
 conda config --set path_conflict prevent
 
+sccache --zero-stats
+
 RAPIDS_PACKAGE_VERSION=$(rapids-generate-version) rapids-conda-retry mambabuild conda/recipes/libcucim
 
+sccache --show-adv-stats
+
 rapids-upload-conda-to-s3 cpp
diff --git a/ci/build_python.sh b/ci/build_python.sh
index 25925f90..4c942e09 100755
--- a/ci/build_python.sh
+++ b/ci/build_python.sh
@@ -20,6 +20,8 @@ conda config --set path_conflict prevent
 
 CPP_CHANNEL=$(rapids-download-conda-from-s3 cpp)
 
+sccache --zero-stats
+
 # TODO: Remove `--no-test` flag once importing on a CPU
 # node works correctly
 RAPIDS_PACKAGE_VERSION=$(head -1 ./VERSION) rapids-conda-retry mambabuild \
@@ -27,4 +29,6 @@ RAPIDS_PACKAGE_VERSION=$(head -1 ./VERSION) rapids-conda-retry mambabuild \
   --channel "${CPP_CHANNEL}" \
   conda/recipes/cucim
 
+sccache --show-adv-stats
+
 rapids-upload-conda-to-s3 python
diff --git a/ci/build_wheel.sh b/ci/build_wheel.sh
index 4005c36d..c72dd946 100755
--- a/ci/build_wheel.sh
+++ b/ci/build_wheel.sh
@@ -5,7 +5,6 @@ set -euo pipefail
 
 package_name="cucim"
 package_dir="python/cucim"
-package_src_dir="${package_dir}/src/${package_name}"
 
 CMAKE_BUILD_TYPE="release"
 
@@ -16,21 +15,42 @@ rapids-generate-version > ./VERSION
 
 RAPIDS_PY_CUDA_SUFFIX="$(rapids-wheel-ctk-name-gen ${RAPIDS_CUDA_VERSION})"
 
-PACKAGE_CUDA_SUFFIX="-${RAPIDS_PY_CUDA_SUFFIX}"
+rapids-logger "Generating build requirements"
 
-# Install pip build dependencies (not yet using pyproject.toml)
 rapids-dependency-file-generator \
-  --file-key "py_build" \
-  --output "requirements" \
-  --matrix "cuda=${RAPIDS_CUDA_VERSION%.*};arch=$(arch);py=${RAPIDS_PY_VERSION}" | tee build_requirements.txt
-pip install -r build_requirements.txt
+  --output requirements \
+  --file-key "py_build_${package_name}" \
+  --file-key "py_rapids_build_${package_name}" \
+  --matrix "cuda=${RAPIDS_CUDA_VERSION%.*};arch=$(arch);py=${RAPIDS_PY_VERSION}" \
+| tee /tmp/requirements-build.txt
+
+rapids-logger "Installing build requirements"
+python -m pip install \
+    -v \
+    --prefer-binary \
+    -r /tmp/requirements-build.txt
+
+sccache --zero-stats
 
 # First build the C++ lib using CMake via the run script
 ./run build_local all ${CMAKE_BUILD_TYPE}
 
+sccache --show-adv-stats
+
 cd "${package_dir}"
 
-python -m pip wheel . -w dist -vvv --no-deps --disable-pip-version-check
+sccache --zero-stats
+
+rapids-logger "Building '${package_name}' wheel"
+python -m pip wheel \
+    -w dist \
+    -v \
+    --no-build-isolation \
+    --no-deps \
+    --disable-pip-version-check \
+    .
+
+sccache --show-adv-stats
 
 mkdir -p final_dist
 python -m auditwheel repair -w final_dist dist/*
diff --git a/dependencies.yaml b/dependencies.yaml
index e25c6f90..5ffab20b 100644
--- a/dependencies.yaml
+++ b/dependencies.yaml
@@ -31,14 +31,14 @@ files:
       - cuda_version
       - docs
       - py_version
-  py_build:
+  py_build_cucim:
     output: pyproject
     pyproject_dir: python/cucim
     extras:
       table: build-system
     includes:
       - rapids_build_setuptools
-  py_rapids_build:
+  py_rapids_build_cucim:
     output: pyproject
     pyproject_dir: python/cucim
     extras: