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Cigar string doesn't match IGV read visualization #1548

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tanyasarkjain opened this issue Aug 20, 2024 · 3 comments
Open

Cigar string doesn't match IGV read visualization #1548

tanyasarkjain opened this issue Aug 20, 2024 · 3 comments

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@tanyasarkjain
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Hi,
I am viewing some aligned reads on IGV as well as programmatically examining the cigar strings in my region of interest. I noticed not all the insertions/deletions present as indicated by the cigar are visible on the reads in IGV. I validated these insertions/deletions do exist using BAMview. Wondering if there is a setting to view all insertions/deletions in all reads? Not sure if some are getting filtered out.

@jrobinso
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What version of IGV are you using? There is an option to hide small indels, enabled by default for long reads. This is controlled by user preference (View > Preferences). See the user documentation for more details.

@tanyasarkjain
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I am using 2.17.3, which setting is it? I have tried adjusting the coverage allele frequency

@jrobinso
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jrobinso commented Aug 21, 2024

The setting is "Hide Indels < show indel threshold"

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